RNA Details
Disease Name
kidney injury
Tissue
kidney
RNA Symbol
circ_0045861
RNA ID
RNA Type
circRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
western blot;bioinformatics analysis;luciferase reporter assays etc.
Target
NA
Pathway
NA
PubMed ID
Title
Hsa_circRNA_0045861 promotes renal injury in ureteropelvic junction obstruction via the microRNA-181d-5p/sirtuin 1 signaling axis
Year
2021
Function
Circ_0045861 may be a novel candidate circRNA in the pathogenesis of ureteropelvic junction obstruction (UPJO) by acting as a pro-apoptotic factor via the miR-181d-5p/SIRT1 axis.